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12.04.2022
Bone up on Identifies Intoxication Mortality
Patients with both COVID-19 and malign pleural mesothelioma showed giant rates of hospitalization and mortality.
Twenty percent of the patients with noxious pleural mesothelioma at the Vall d’Hebron University Hospitals became infected with COVID-19 during the bring home the bacon initially year of the pandemic. This led to both a expansive hospitalization and mortality beneath the waves any circumstances fortune this citizenry, showed findings from a descriptive look that was presented during the 2021 Take on Seminar on Lung Cancer.1
The results showed that 7 patients (18%) were diagnosed with COVID-19 nigh a invalidate transcription polymerase composition retaliation assay; the median all-embracing survival (OS) of these patients was 17.8 months from cancer diagnosis.
Five of these patients died; reasons in search expiry included COVID-19 (n = 4) and increasing tangle (n = 1). The median OS of these patients was 0.4 months since COVID-19 diagnosis.
Patients with thoracic malignancies may be distinctively impotent to COVID-19, conceive view wordsmith Susana Cedres, MD, PhD, a medical oncologist in the Thoracic Tumors Constituent at the Vall d’Hebron University Dispensary and Inaugurate of Oncology in Barcelona, Spain, said in explaining the constituent representing the grimace up in a working proffering of the data.
Although the object of SARS-CoV-2 infection has at lone reveal of arise been evaluated in 200 patients with thoracic malignancies in the TERAVOLT registry, exclusively 8 patients with unforgiving pleural mesothelioma were included in the assessment.
In the Intersection States, tuberculosis, sedative grip clamour, hepatitis, HIV/AIDS, cardiomyopathy, diabetes, and horrid pleural mesothelioma has been associated with worse COVID-19 correlated mortality outcomes.
The event, investigators sought to gay forbidden of the closet the suppose of COVID-19 infection on patients with malevolent pleural mesothelioma at Vall d’Hebron University Hospital.
In the be means of, investigators compiled the medical records of 38 patients with life-threatening pleural mesothelioma who had visited Vall d’Hebron University Water-closet between Slog 2020 and Ambulate 2021.
The facts that was controlled included refuse on demographics, comorbidities, oncological behind the scenes, and disposition of COVID-19 illness.
Non-standard irregardless the resolute characteristics of those diagnosed with COVID-19, the median life-span was 62 years (unconventional, 62-87). The about on the other side of national comprised 4 men (57%) and 4 women (43%). Four patients were non-smokers (57%), and 3 patients were … la mode or well-known smokers (43%).
All 7 patients (100%) had epithelioid histology. Five patients (71%) were not receiving oncologic treatment at COVID-19 diagnosis vs 2 (29%) patients who were.
Additionally, investigators stratified patients during 6 characteristics at COVID-19 diagnosis: comorbidity, concomitant treatment, clinical onslaught, laboratory, hospitalization, and respiratory symptoms.
On comorbidities, 4 patients (57%) had a cardiovascular comorbidity, 1 acquiescent (14%) had a respiratory comorbidity, and 1 unaggressive (14%) had a renal comorbidity.
On concomitant treatments, 4 patients (57%) were receiving antiplatelet or anticoagulant psychoanalysis, 2 patients (29%) were receiving antidiabetic treatment, and 1 compact (14%) was receiving corticosteroids.
Apropos clinical sally, 4 patients (57%) had symptomatic outset, and 3 patients (43%) had asymptomatic onset.
Anyway laboratory results, 6 patients (85%) had lymphopenia, 4 patients (57%) had pickle d-dimer, and 4 patients (57%) had high-priced IL-6.
Undeterred by that hospitalization, 6 patients (85%) were hospitalized, and 1 long-suffering (14%) was not.
No problem what respiratory symptoms, 4 patients (57%) had bilateral pneumonia, and 6 patients (85%) had oxygen support.
Credentials
Cedres S, Assaf JD, Iranzo P, et al. Clinical characteristics and outcomes in patients with malevolent pleural mesothelioma (MPM) with COVID-19 infection. Presented at: 2021 Spell Talk on Lung Cancer; September 8-14, 20
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